research areas - health

ESIEE Paris Teacher-Researchers participate in research programs in the health field, in close collaboration with companies and various university hospital centres (CHU). This work can be found in the LIGM laboratory with the development of image processing algorithms and in the ESYCOM laboratory with the design and production of innovative microsensors for the environment and health. These activities can be grouped around two themes where teacher-researchers have acquired a scientific level of excellence:

Medical imaging

ESIEE Paris researchers have acquired international renown in the field of medical image processing, and have long-standing collaborations with healthcare industries and medical teams, for example:

  • with the Henri Mondor University Hospital in Créteil, image segmentation and restoration methods
  • with SIEMENS Research Princeton for the detection of fine structures, such as blood vessels, in 2D and 3D images
  • with GENERAL ELECTRIC, geometric and physical modeling of the cerebral vascular network, with the universities of Reims, Strasbourg and Grenoble, and the company KitWare

Sensors and instrumentation for health

Cutting-edge technological innovations based on the use of micro-technologies in connection with the ESIEE Paris clean room lead to scientific research on the creation of interfaces with the environment and sensors deployed on and in the human body, as by example:

Micro-electrode networks (or MEA -Micro Electrode Arrays) for recording and stimulating neural signals or for the development of retinal implants, in collaboration with the Institut de la Vision, INSERM, CNRS and the CEA. An ERC starting grant was started in 2018 specifically on this action and should allow the establishment of a MEMS Diamond technology sector
Chip-based laboratories that allow analysis of the environment for the detection of pollutants or particles, whether in liquid or gaseous media.

Examples of research projects

ERC Starting Grant - NEURODIAM

This European-funded excellence project consists of designing new thin ECoG (ElectroCorticoGraphy) implants based on synthetic diamond nano structuring combined with microtechnology. The objective of the NEURODIAM project is to develop an all-diamond implant for neuronal applications.

At a time when central nervous system dysfunctions affect an ever-growing portion of the world's population, a major challenge is to advance our understanding of brain function. Thanks to implants of the microelectrode type, it is currently possible to restore neurological functions in disabled patients, such as visual perception or movements induced in prostheses. This project is developed in the clean rooms ESIEE Paris.

Funding: ERC "Starting Grant"
Project leaders: Lionel Rousseau, Researcher and Head of the White Room ESIEE Paris, ESYCOM Laboratory
Date: 2018-2023
Partners: Institut de la Vision, CEA List

HFLOW: Modeling of biological tissue perfusion

Objective: this research program addresses the problem of modelling fine tissue perfusion from an anatomical model of the tissue and of the vascular system supplying blood to the tissue. The project focuses more particularly on the modelling of the perfusion of the cardiac myocardium using a model of the coronary arteries supplying the myocardium coupled to a porous medium, modelling the microvasculature.

Project leader: Laurent Najman, Teacher-Researcher of the Computer Science Department, LIGM Laboratory
Funding: Collaboration
Date: 2015 - 2021
Partners: Inria, HeartFlow

Proteus: Multisensor platform for monitoring water quality (Adaptive microfluidic - and nano - enabled smart systems for water quality sensing)

Objective: water management requires massive and inexpensive monitoring, which means that differentiated and evolving requirements must be faced. The PROTEUS project aims to develop a platform of reconfigurable microfluidic and nanometric sensors for cognitive monitoring of water quality. The challenge is to bring together chemical sensors based on carbon nanotubes, physical and rheological resistive sensors of the MEMS type associated with a functionalizable CMOS circuit. The microfabrication resources available within ESIEE Paris (White Room) allow the creation of this type of multi-sensor platform.

Project leader: Tarik Bourouina, Teacher-Researcher of the Health-Energy-Environment Department, ESYCOM Laboratory
Funding: European, H2020 Program
Date: 2015-2020
Partners: Gustave Eiffel University (Ifsttar), Technological University of Lisbon, Easy Global Market, Wings ICT, University of Perugia ...